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                            id="yiv6073898175yui_3_16_0_1_1496925568860_6073"
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                            text-decoration-style: initial;
                            text-decoration-color: initial;"><b
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6074"
                              style="-webkit-padding-start: 0px;
                              font-size: 12px;">Call for Papers -
                              Research Topic: "</b><b
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6077"
                              style="-webkit-padding-start: 0px;"><font
id="yiv6073898175yui_3_16_0_1_1496925568860_6850"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6851"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">Computational
                                  Approaches for Signal Detection and
                                  Management in Pharmacovigilance</span></font></b><b
id="yiv6073898175yui_3_16_0_1_1496925568860_6078"
                              style="-webkit-padding-start: 0px;
                              font-size: 12px;">"<br
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6079"
                                style="-webkit-padding-start: 0px;">
                            </b><font
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6450"
                              style="-webkit-padding-start: 0px;"
                              face="HelveticaNeue, Helvetica Neue,
                              Helvetica, Arial, Lucida Grande,
                              sans-serif"><span
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6451"
                                style="-webkit-padding-start: 0px;
                                font-size: 12px;"><a rel="nofollow"
                                  target="_blank"
                                  href="http://journal.frontiersin.org/journal/pharmacology"
id="yiv6073898175yui_3_16_0_1_1496925568860_6735"
                                  class="yiv6073898175enhancr2_93009ddf-1f9f-a614-2d5c-62ce3e299859"
                                  style="-webkit-padding-start: 0px;
                                  margin: 0px; padding: 0px;
                                  text-decoration: underline;
                                  background: transparent; color:
                                  rgb(25, 106, 212); outline: none;">Frontiers
                                  in Pharmacology</a></span></font><font
id="yiv6073898175yui_3_16_0_1_1496925568860_6452"
                              style="-webkit-padding-start: 0px;"
                              face="HelveticaNeue, Helvetica Neue,
                              Helvetica, Arial, Lucida Grande,
                              sans-serif"><span
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6453"
                                style="-webkit-padding-start: 0px;
                                font-size: 12px;"> (<b
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_11166"
                                  style="-webkit-padding-start: 0px;">Impact
                                  factor 2015</b>:<span
                                  class="Apple-converted-space"> </span><b
                                  id="yui_3_16_0_1_1496925568860_14520"
                                  style="-webkit-padding-start: 0px;">4.418</b>)</span></font><br
id="yiv6073898175yui_3_16_0_1_1496925568860_6082"
                              style="-webkit-padding-start: 0px;">
                            <br
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6083"
                              style="-webkit-padding-start: 0px;">
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6454"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6455"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6456"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">Historically, the
                                  main knowledge source for
                                  pharmacovigilance consists of
                                  spontaneous case reports issued by
                                  healthcare professionals and patients
                                  and these case reports are usually
                                  manually reviewed by evaluators in a
                                  qualitative way. Pharmacovigilance has
                                  for a long time been confined to a
                                  role of passive surveillance of
                                  adverse drug reactions (ADRs), which
                                  means that measures to look for ADRs
                                  are limited to the encouragement of
                                  health professionals and others to
                                  report safety issues in order to alert
                                  the health authorities. This role is
                                  indispensable but should now be
                                  associated to a “pro-active” approach,
                                  in order to identify potential
                                  problems and safety risks before they
                                  emerge into crises. Additionally,
                                  under declaration is a major drawback
                                  limiting the ability of
                                  pharmacovigilance to process the
                                  evaluation of case reports and to
                                  detect early signals.</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6454"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;"><br
                                    style="-webkit-padding-start: 0px;">
                                </span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6457"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6458"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6459"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">In this context, the
                                  development of new data analytic
                                  methods and the availability of more
                                  efficient computing resources allows
                                  considering new data sources for
                                  pharmacovigilance, such as lectronic
                                  health records, administrative claims
                                  systems, case-mix databases, social
                                  media, search log data and the medical
                                  literature. New data mining techniques
                                  are being implemented in order to
                                  detect safety signals in dominant
                                  pharmacovigilance data sources as well
                                  as in emerging data sources. Notable
                                  systematic efforts relevant with the
                                  Research Topic have already been
                                  conducted in projects such as the
                                  Observational Medical Outcomes
                                  Partnership (OMOP)<span
                                    class="Apple-converted-space"> </span><a
                                    rel="nofollow" target="_blank"
                                    href="http://omop.org/"
                                    id="yiv6073898175yui_3_16_0_1_1496925568860_7799"
                                    style="-webkit-padding-start: 0px;
                                    margin: 0px; padding: 0px;
                                    text-decoration: underline;
                                    background: transparent; color:
                                    rgb(25, 106, 212); outline: none;">http://omop.org</a>,
                                  the Pharmacoepidemiological Research
                                  on Outcomes of Therapeutics by a
                                  European Consortium (PROTECT)<span
                                    class="Apple-converted-space"> </span><a
                                    rel="nofollow" target="_blank"
                                    href="http://www.imi-protect.eu/"
                                    id="yiv6073898175yui_3_16_0_1_1496925568860_7798"
                                    style="-webkit-padding-start: 0px;
                                    margin: 0px; padding: 0px;
                                    text-decoration: underline;
                                    background: transparent; color:
                                    rgb(25, 106, 212); outline: none;">http://www.imi-protect.eu</a>,
                                  the EU-ADR European project<a
                                    rel="nofollow" target="_blank"
                                    href="https://bioinformatics.ua.pt/euadr/Welcome.jsp"
id="yiv6073898175yui_3_16_0_1_1496925568860_7862"
                                    style="-webkit-padding-start: 0px;
                                    margin: 0px; padding: 0px;
                                    text-decoration: underline;
                                    background: transparent; color:
                                    rgb(25, 106, 212); outline: none;">https://bioinformatics.ua.pt/euadr/Welcome.jsp</a> ,
                                  the U.S. Food and Drug
                                  Administration’s Mini-Sentinel program<a
                                    rel="nofollow" target="_blank"
                                    href="https://www.sentinelinitiative.org/"
id="yiv6073898175yui_3_16_0_1_1496925568860_9126"
                                    style="-webkit-padding-start: 0px;
                                    margin: 0px; padding: 0px;
                                    text-decoration: underline;
                                    background: transparent; color:
                                    rgb(25, 106, 212); outline: none;">https://www.sentinelinitiative.org</a>,
                                  and the European Web-RADR project<span
                                    class="Apple-converted-space"> </span><a
                                    rel="nofollow" target="_blank"
                                    href="https://web-radr.eu./"
                                    class="yiv6073898175"
                                    id="yiv6073898175yui_3_16_0_1_1496925568860_7590"
                                    style="-webkit-padding-start: 0px;
                                    margin: 0px; padding: 0px;
                                    text-decoration: underline;
                                    background: transparent; color:
                                    rgb(25, 106, 212); outline: none;">https://web-radr.eu/</a>.</span></font></div>
                            <div
                              id="yiv6073898175yui_3_16_0_1_1496925568860_7754"
                              style="-webkit-padding-start: 0px;"><br
                                style="-webkit-padding-start: 0px;">
                            </div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6460"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6461"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6462"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">The objective of
                                  this Research Topic is to describe the
                                  state of advancement of innovative
                                  research that relies heavily on data
                                  processing for analyzing all possible
                                  (traditional and emerging) sources of
                                  knowledge for pharmacovigilance.</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6460"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;"><br
                                    style="-webkit-padding-start: 0px;">
                                </span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6460"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_9057"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_9056"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">This includes but is
                                  not limited to:</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6463"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6464"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6465"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6466" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Analyzing
                                  big data such as patients’ posts
                                  extracted from forums on the internet
                                  as well as large observational
                                  databases for signal detection</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6467"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6468"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6469"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6470" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Innovative
                                  systems considering other data sources
                                  than case reports, e.g. medical
                                  literature</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6471"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6472"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6473"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6474" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Combining
                                  multiple healthcare databases</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6475"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6476"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6477"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6478" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Novel
                                  computational signal detection methods
                                  for spontaneous reporting systems</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6479"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6480"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6481"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6482" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Influence
                                  of the MedDRA hierarchy on case
                                  retrieval and signal detection</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6483"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6484"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6485"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6486" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Knowledge
                                  engineering techniques for modelling
                                  and extracting knowledge on ADRs</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6487"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6488"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6489"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6490" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Joint
                                  signal detection through integrative
                                  analysis of multiple, heterogeneous
                                  data sources</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6491"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6492"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6493"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6494" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Computational
                                  methods for signal verification /
                                  causality assessment</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6495"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6496"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6497"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6498" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Evaluation
                                  / comparative studies of computational
                                  signal detection methods</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6499"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6500"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6501"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6502" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Novel
                                  tools (e.g. mobile apps and
                                  applications at the point-of-care)
                                  aiming to reinforce/facilitate ADR
                                  reporting</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6503"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6504"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6505"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6506" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Extraction
                                  of ADR knowledge from clinical notes
                                  in the electronic health record</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6507"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6508"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6509"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6510" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Substantiation
                                  of drug safety signals, i.e. providing
                                  a biological explanation by exploring
                                  mechanistic connections that might
                                  explain why a drug produces a specific
                                  ADR</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6511"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6512"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6513"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6514" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Public
                                  resources intended to support
                                  computational process in
                                  pharmacovigilance</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6515"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6516"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6517"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6518" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Successful
                                  case studies concerning the
                                  application of computational methods
                                  in pharmacovigilance</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6519"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6520"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6521"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">•<span id="yiv6073898175yui_3_16_0_1_1496925568860_6522" style="-webkit-padding-start: 0px; white-space: pre-wrap;">    </span>Opinion
                                  and review papers in the domain</span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6523"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6524"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6525"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;"><br
                                    id="yiv6073898175yui_3_16_0_1_1496925568860_6526"
                                    style="-webkit-padding-start: 0px;">
                                </span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6527"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_6528"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_6529"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;"><b
                                    id="yiv6073898175yui_3_16_0_1_1496925568860_9085"
                                    style="-webkit-padding-start: 0px;">Keywords</b>:
                                  Pharmacovigilance, Signal Detection,
                                  Computational Methods, Data Analytics,
                                  Knowledge Engineering</span></font></div>
                          </div>
                          <div dir="ltr"
                            id="yiv6073898175yui_3_16_0_1_1496925568860_6073"
                            style="-webkit-padding-start: 0px;
                            text-align: start; color: rgb(0, 0, 0);
                            font-family: "Helvetica Neue",
                            Helvetica, Arial, "Lucida Grande",
                            sans-serif; font-size: 13px; font-style:
                            normal; font-variant-ligatures: normal;
                            font-variant-caps: normal; font-weight:
                            normal; letter-spacing: normal; orphans: 2;
                            text-indent: 0px; text-transform: none;
                            white-space: normal; widows: 2;
                            word-spacing: 0px;
                            -webkit-text-stroke-width: 0px;
                            background-color: rgb(255, 255, 255);
                            text-decoration-style: initial;
                            text-decoration-color: initial;"><br
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6100"
                              style="-webkit-padding-start: 0px;">
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_8519"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_8520"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_8521"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;"><b
                                    id="yiv6073898175yui_3_16_0_1_1496925568860_8719"
                                    style="-webkit-padding-start: 0px;">Submission
                                    Deadlines:</b></span></font></div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_8522"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><span
                                id="yiv6073898175yui_3_16_0_1_1496925568860_9058"
                                style="-webkit-padding-start: 0px;
                                font-size: 12px;">July 15, 2017:<span id="yiv6073898175yui_3_16_0_1_1496925568860_11292" style="-webkit-padding-start: 0px; white-space: pre-wrap;"> </span></span><span
id="yiv6073898175yui_3_16_0_1_1496925568860_8660"
                                style="-webkit-padding-start: 0px;
                                font-size: 12px;">Abstract</span><br
                                style="-webkit-padding-start: 0px;">
                            </div>
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_8530"
                              style="-webkit-padding-start: 0px;
                              text-align: start;"><font
                                id="yiv6073898175yui_3_16_0_1_1496925568860_8531"
                                style="-webkit-padding-start: 0px;"
                                face="HelveticaNeue, Helvetica Neue,
                                Helvetica, Arial, Lucida Grande,
                                sans-serif"><span
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_8532"
                                  style="-webkit-padding-start: 0px;
                                  font-size: 12px;">October 02, 2017:<span id="yiv6073898175yui_3_16_0_1_1496925568860_8661" style="-webkit-padding-start: 0px; white-space: pre-wrap;"> </span>Manuscript</span></font></div>
                            <br
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6105"
                              style="-webkit-padding-start: 0px;">
                            <font
                              id="yiv6073898175yui_3_16_0_1_1496925568860_8534"
                              style="-webkit-padding-start: 0px;"
                              face="HelveticaNeue, Helvetica Neue,
                              Helvetica, Arial, Lucida Grande,
                              sans-serif"><span
                                id="yiv6073898175yui_3_16_0_1_1496925568860_8535"
                                style="-webkit-padding-start: 0px;
                                font-size: 12px;"><b
                                  id="yiv6073898175yui_3_16_0_1_1496925568860_8678"
                                  style="-webkit-padding-start: 0px;">Guest
                                  Editors:</b></span></font></div>
                          <div dir="ltr"
                            id="yiv6073898175yui_3_16_0_1_1496925568860_6073"
                            style="-webkit-padding-start: 0px;
                            text-align: start; color: rgb(0, 0, 0);
                            font-family: "Helvetica Neue",
                            Helvetica, Arial, "Lucida Grande",
                            sans-serif; font-style: normal;
                            font-variant-ligatures: normal;
                            font-variant-caps: normal; font-weight:
                            normal; letter-spacing: normal; orphans: 2;
                            text-indent: 0px; text-transform: none;
                            white-space: normal; widows: 2;
                            word-spacing: 0px;
                            -webkit-text-stroke-width: 0px;
                            background-color: rgb(255, 255, 255);
                            text-decoration-style: initial;
                            text-decoration-color: initial; font-size:
                            12px;">
                            <div dir="ltr"
                              id="yiv6073898175yui_3_16_0_1_1496925568860_8156"
                              style="-webkit-padding-start: 0px;
                              text-align: start;">    Cedric Bousquet,
                              Centre Hospitalier Universitaire de
                              Saint-Étienne, Saint-Étienne, France</div>
                                Marie-Christine Jaulent, INSERM, Paris,
                            France</div>
                          <div dir="ltr"
                            id="yiv6073898175yui_3_16_0_1_1496925568860_6073"
                            style="-webkit-padding-start: 0px;
                            text-align: start; color: rgb(0, 0, 0);
                            font-family: "Helvetica Neue",
                            Helvetica, Arial, "Lucida Grande",
                            sans-serif; font-size: 13px; font-style:
                            normal; font-variant-ligatures: normal;
                            font-variant-caps: normal; font-weight:
                            normal; letter-spacing: normal; orphans: 2;
                            text-indent: 0px; text-transform: none;
                            white-space: normal; widows: 2;
                            word-spacing: 0px;
                            -webkit-text-stroke-width: 0px;
                            background-color: rgb(255, 255, 255);
                            text-decoration-style: initial;
                            text-decoration-color: initial;"><font
                              id="yiv6073898175yui_3_16_0_1_1496925568860_8325"
                              style="-webkit-padding-start: 0px;"
                              face="HelveticaNeue, Helvetica Neue,
                              Helvetica, Arial, Lucida Grande,
                              sans-serif"><span
                                id="yiv6073898175yui_3_16_0_1_1496925568860_8326"
                                style="-webkit-padding-start: 0px;
                                font-size: 12px;">    Vassilis Koutkias,
                                Institute of Applied Biosciences, Centre
                                for Research & Technology Hellas,
                                Thessaloniki, Greece</span></font><br
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6112"
                              style="-webkit-padding-start: 0px;">
                            <br
                              id="yiv6073898175yui_3_16_0_1_1496925568860_6113"
                              style="-webkit-padding-start: 0px;">
                            <font
                              id="yiv6073898175yui_3_16_0_1_1496925568860_8327"
                              style="-webkit-padding-start: 0px;"
                              face="HelveticaNeue, Helvetica Neue,
                              Helvetica, Arial, Lucida Grande,
                              sans-serif"><span
                                id="yiv6073898175yui_3_16_0_1_1496925568860_8328"
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