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Curator prediction of NOT kinase activity

Emily Dimmer edimmer at
Wed Mar 8 02:48:27 PST 2006


One of our annotators, who is an expert on protein kinases, has looked 
at the sequence of a putative protein kinase and from noticing a couple 
of amino acids changes at its active site, has predicted that it does 
not possess any kinase activity - she did not use any software and there 
is no published work on this protein.
Do you think this type of annotation should be represented in GO (we 
feel this annotation is of high quality and adds valuable information to 
a protein which has not yet been characterized), and if so how should 
this annotation be shown?


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