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allergene annotation

Jane Lomax jane at ebi.ac.uk
Tue Mar 14 05:53:16 PST 2006


Unfortunately that term only works where one organism is living in 
symbiosis with another organism (e.g. host/pathogen) which is why I 
suggested that new term...


On Tue, 14 Mar 2006, Harold Drabkin wrote:

> But, I did find this term, and related?
> 
> GO term: 	*induction of host defense response*
> GO id: 	*GO:0044416*
> Definition: 	*The elicitation by an organism of the defense response of 
> the host. The host is defined as the larger of the organisms involved in 
> a symbiotic interaction. *
> 
> 
> which I think might be more in line with a direct annotation to 
> something like this???
> 
> 
> Harold Drabkin wrote:
> > I would not; they are the a cause, but they are not involved in the 
> > process (which is not occurring in the plant).
> > The GO is used to indicate the normal function and process of a gene 
> > product. You need to look at it from the point of view of the organism 
> > that produces the gene product. If these perform some function for the 
> > plant, that is what you would annotate them to. Perhaps there are 
> > terms associated with defense in a plant (ie, along the lines of 
> > something that is released to deter the plant from being eaten???__?
> >
> >
> >
> > adepto at cribi.unipd.it wrote:
> >> Hi All
> >> I have to annotate plant genes described as "allergenic peptides" in 
> >> pFam these
> >> genes are described as:
> >> "Allergies are hypersensitivity reactions of the immune system to 
> >> specific
> >> substances called allergens (such as pollen, stings, drugs, or food) 
> >> that, in
> >> most people, result in no symptoms. A nomenclature system has been 
> >> established
> >> for antigens (allergens) that cause IgE-mediated atopic allergies in 
> >> humans..."
> >>
> >> So, where may I annotate these allergenes? It is GO:0016068 (type I
> >> hypersensitivity) the right term? Thanks in advance.
> >> Alessandro
> >>   
> >
> 
> 

Dr Jane Lomax
GO Editorial Office
EMBL-EBI
Wellcome Trust Genome Campus
Hinxton
Cambridgeshire, UK
CB10 1SD

p: +44 1223 492516
f: +44 1223 494468




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