Search Mailing List Archives
hjd at informatics.jax.org
Tue Mar 14 06:06:30 PST 2006
Yes, a new term would work much better. However, it may or may not be
the "normal " function or process.
A virus or symbiont host interaction is a bit different, because those
interactions are most likely critical for the life cycle (eg, if you
don't have a host, the virus can't replicate, etc.). Many people are
allergic to gluten, but is that a normal function/process of gluten?
Jane Lomax wrote:
> Unfortunately that term only works where one organism is living in
> symbiosis with another organism (e.g. host/pathogen) which is why I
> suggested that new term...
> On Tue, 14 Mar 2006, Harold Drabkin wrote:
>> But, I did find this term, and related?
>> GO term: *induction of host defense response*
>> GO id: *GO:0044416*
>> Definition: *The elicitation by an organism of the defense response of
>> the host. The host is defined as the larger of the organisms involved in
>> a symbiotic interaction. *
>> which I think might be more in line with a direct annotation to
>> something like this???
>> Harold Drabkin wrote:
>>> I would not; they are the a cause, but they are not involved in the
>>> process (which is not occurring in the plant).
>>> The GO is used to indicate the normal function and process of a gene
>>> product. You need to look at it from the point of view of the organism
>>> that produces the gene product. If these perform some function for the
>>> plant, that is what you would annotate them to. Perhaps there are
>>> terms associated with defense in a plant (ie, along the lines of
>>> something that is released to deter the plant from being eaten???__?
>>> adepto at cribi.unipd.it wrote:
>>>> Hi All
>>>> I have to annotate plant genes described as "allergenic peptides" in
>>>> pFam these
>>>> genes are described as:
>>>> "Allergies are hypersensitivity reactions of the immune system to
>>>> substances called allergens (such as pollen, stings, drugs, or food)
>>>> that, in
>>>> most people, result in no symptoms. A nomenclature system has been
>>>> for antigens (allergens) that cause IgE-mediated atopic allergies in
>>>> So, where may I annotate these allergenes? It is GO:0016068 (type I
>>>> hypersensitivity) the right term? Thanks in advance.
> Dr Jane Lomax
> GO Editorial Office
> Wellcome Trust Genome Campus
> Cambridgeshire, UK
> CB10 1SD
> p: +44 1223 492516
> f: +44 1223 494468
More information about the go-discuss