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neural crest cell maturation vs. specific cell type differentiation

Melissa Haendel mhaendel at
Wed Mar 15 12:25:41 PST 2006

Hi, I wanted to send this set of questions separately than my previous 
email as I think they will require discussion.

I need a term that represents the final stages of neural crest cell 
differentiation into their derivatives.  I could annotate to pigment 
cell differentiation, etc, but it would be better to say that all 
derivatives don't begin their differentiation.  Once neural crest cells 
begin to differentiate into their derivatives, they are no longer called 
neural crest cells.  So, would the term "neural crest cell maturation' 
with the following definition work?  "The process leading to the 
attainment of the full functional capacity of a neural crest cell 
derivative. This process is independent of morphogenetic change."  I 
have added the word derivative, but I don't know if this will fly.  
Thought I would email the listserve for advice before making a request.

How have any of you dealt with differentiation into derivative cell 
types with different names in the past? 

Any advice is much appreciated.

Thanks, Melissa Haendel

Melissa Haendel, Ph.D.


ZFIN Scientific Curator

Zebrafish Information Network

5291 University of Oregon

Eugene, OR 97403-5291

Phone: (541) 346-5108

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