allergene annotation

[Pascale Gaudet]

I think an allergy is an abnormal process, isn't it? So it should be 
annotated. I dont think it's a defense response??

Pascale


At 08:40 AM 3/14/2006 -0500, Harold Drabkin wrote:
>I would not; they are the a cause, but they are not involved in the 
>process (which is not occurring in the plant).
>The GO is used to indicate the normal function and process of a gene 
>product. You need to look at it from the point of view of the organism 
>that produces the gene product. If these perform some function for the 
>plant, that is what you would annotate them to. Perhaps there are terms 
>associated with defense in a plant (ie, along the lines of something that 
>is released to deter the plant from being eaten???__?
>
>
>
>adepto at cribi.unipd.it wrote:
>>Hi All
>>I have to annotate plant genes described as "allergenic peptides" in pFam 
>>these
>>genes are described as:
>>"Allergies are hypersensitivity reactions of the immune system to specific
>>substances called allergens (such as pollen, stings, drugs, or food) that, in
>>most people, result in no symptoms. A nomenclature system has been 
>>established
>>for antigens (allergens) that cause IgE-mediated atopic allergies in 
>>humans..."
>>
>>So, where may I annotate these allergenes? It is GO:0016068 (type I
>>hypersensitivity) the right term? Thanks in advance.
>>Alessandro
>>