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GO term for innervation

Midori Harris midori at ebi.ac.uk
Thu Mar 29 07:53:53 PDT 2007


Sure; thanks!

m

On Thu, 29 Mar 2007, Susan Tweedie wrote:

> Thanks, Midori. That would be good. Shall I add it to source forge?
>
> Susan
>
> On Thu, 2007-03-29 at 14:36 +0100, Midori Harris wrote:
>> I think we could improve the wording of the 'axonogenesis' definition
>> anyway, to make it more consistent with the 'axon' definition in the
>> component ontology (and correct the punctuation error).
>>
>> Suggestion:
>>
>> "Generation of an axon, a long process that extends from the cell body of
>> a neuron and conducts nerve impulses, which usually travel away from the
>> cell body to the terminals and varicosities and towards target cells."
>>
>> But I don't know whether 'innervation' is exactly the same; I'll go with
>> whatever the innervation experts say.
>>
>> midori
>>
>> On Thu, 29 Mar 2007, Susan Tweedie wrote:
>>
>>> We are struggling to decide if the GO term 'axonogenesis' is exactly
>>> equivalent to 'innervation' (as in the process involving nerve
>>> projection and connection with a target - and as used in the mammalian
>>> phenotype term 'abnormal innervation' MP:0002184). Axonogenesis has the
>>> approriate child terms of  'axon guidance' and 'axon target recogintion'
>>> but I'm put off by the word 'towards' in the definition:
>>>
>>> Generation of a long process of a neuron, that carries efferent
>>> (outgoing) action potentials from the cell body towards target cells.
>>>
>>> If it is the same thing, then I'll make an sf item to add 'innervation'
>>> as an exact synonym.
>>>
>>>
>>> Thanks,
>>>
>>> Susan (and George)
>>>
>



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