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Mon Feb 19 08:34:19 PST 2001
As currently defined the Gene Ontology project is not a database of
proteins; rather a network of processes, functions and cellular
components. The gene products that are associated to the GO are not
"part" of GO. That is the gene products are defined by the model
> I think that the point of the GO would be to describe the components
> involved in the process, but not the targets; so, one would have
> terms to describe the enzymes involved in trans-splicing,splicing,
> but not every single instance of transcripts that get spliced, etc. ?
> >And along with all this, where does trans-splicing fit into the picture?
> >Nilsen TW. trans-splicing: an update. Molecular & Biochemical
> >Parasitology. 73:1-6, 1995.
> > and for proteins
> >Perler FB. A natural example of protein trans-splicing. Trends
> >Biochem. Sci. 24:209-11, 1999).
> Harold J. Drabkin, Ph.D.
> Scientific Curator
> Mouse Genome Informatics
> The Jackson Laboratory
> 600 Main Street
> Bar Harbor, ME 04609
> 207-288-6650 (voice)
> 207-288-6131 (fax)
> hjd at informatics.jax.org
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