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[Fwd: Genotype to Pheotype Workshop]

Helen Parkinson parkinson at ebi.ac.uk
Wed Feb 6 02:34:32 PST 2002


Forwarded on behalf of Robert Stevens.

Extended call for abstracts: Abstracts for this one day
meeting, which is part of Manchester Bioinformatics Week,
can now be submitted until 11 February 2002.

A one-day workshop on "From Genotype to Phenotype Linking
Bioinformatics and Medical
Informatics Ontologies"

(Chaired by Alan Rector and Robert Stevens)

 is being held as part of Manchester Bioinformatics Week -
Easter 2002. The details on the workshop may be found at
http://www.biomed2.man.ac.uk/bioinfconferen/default.htm.

The medical informatics community has had an interest and a
wealth of experience in developing and using ontologies,
that stretches back over  many decades. The younger
Bioinformatics community has also indicated a growing
interest in the subject area. There is both a common
interest and a diversity in these fields, that together, we
hope can be of mutual interest and benefit to both
communities.

Bioinformatics ontologies have described knowledge of the
genotype of organisms: Their molecular biology, function,
pathways, molecular structures and general classifications.
Medical informatics ontologies have described knowledge
about phenotype: Appearance, anatomy, disease, etc. of
mainly one organism -- Human, but occaisionally others. the
genotype is the genes and genetics, together with associated
cellular machinery, that gives rise to those phenotypes.  As
Bioinformatics gears up to manage, store and analyse data
and knowledge from new experimental techniques, such as
micro array gene expression, the discipline is becoming more
interested in linking knowledge of genotype to the phenotype
governed by that gene expression -- or more broadly in
linking  molecular  - genetic, genomic and proteomic -
mechanisms to their consequences for  physiology and
pathology and ultimately clinical medicine - i.e. the
health and disease of organs and organisms.  Making this
linkage is a key step in understanding the mechanisms of
known drugs and discovering new ones.

The linking of genotype and phenotype ontologies offers
interesting opportunities for collaboration  between Medical
Informatics and Bioinformatics.  I hope that you will be
able to attend and I also hope that you can submit an
abstract to the workshop.
Registration and Submission of Abstracts is possible via the
web
site. The deadline for receipt of abstracts is 25th January
2002.
There are reduced fees for payments received before this
date.



 Dr. Robert StevensDepartment of Computer ScienceKilburn
BuildingUniversity of ManchesterManchesterM13 9PLTelephone:
+44 (0)161 275 6251Web: http://img.cs.man.a.uk/stevensemail:
robert.stevens at cs.man.ac.uk


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