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What is meant by INNER NO OUTER gene product

K. B. Cohen kevin.cohen at
Wed Jan 7 08:20:18 PST 2004

here's a link to the abstract of an article on this gene:

INNER NO OUTER regulates abaxial- adaxial patterning in Arabidopsis ovules.

Villanueva JM, Broadhvest J, Hauser BA, Meister RJ, Schneitz K, Gasser CS.

Section of Molecular and Cellular Biology, University of California, 
Davis, California 95616, USA.

The Arabidopsis INNER NO OUTER (INO) gene is essential for formation and 
asymmetric growth of the ovule outer integument. INO encodes a member of 
the newly described YABBY family of putative transcription factors that 
contain apparent Cys(2)-Cys(2) zinc-finger domains and regions of 
similarity to the high mobility group (HMG) transcription factors. In 
wild-type plants, INO is expressed specifically on one side of the 
central region of each ovule primordium in the cells that give rise to 
the outer integument. Alterations in the INO expression pattern in 
mutant backgrounds implicate INO as a positive regulator of its own 
expression, and ANT, HLL, BEL1, and SUP as direct or indirect negative 
regulators that help to establish the spatial pattern of INO expression. 
We hypothesize that INO is necessary for polarity determination in the 
central part of the ovule. Maintenance of polarity in other parts of ino 
ovules indicates the existence of additional regulators and provides 
further evidence that the ovule is a compound structure.

great name!


J Clark wrote:

> INNER NO OUTER is the name of a gene product that has been annotated 
> to those terms.

Kevin B. Cohen

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