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GO question

Mary Dolan Mary_Dolan at
Thu Jun 24 14:15:40 PDT 2004

Antony Rodriguez <ar3 at> writes:
>Dear GO members,
>I came accross the GO website and wanted to ask you guys a specific 
>I have a small set of genes from humans (approx 200) and I retrieved 
>biological processes and molecular functions for each one.  My question 
>is, how or where do I go to compare the frequency (abundances) for each 
>category within this group with that of the entire genome as a whole?  
>For instance if in this set there are 20 out of 200 genes with a 
>'transport' GO:0006810 biological process and I wanted to determine if 
>this is unusually high fraction within my sample size as compared to 
>the total fraction of 'transport' genes in the entire human genome 
>where would I search for such information?
>Thanks for the help,
>Antony Rodriguez, Ph.D.

Joel Richardson here at jax has a web tool that might do what you are asking for. 
VLAD - VisuaL Annotation Display - is a tool for visualizing GO annotations. The annotation data are a subset of those available at the GO web site (MGI, RGD, Human, Flybase, SGD, or ZFIN). You specify an annotation data set and a set of genes, and
the tool will produce a graphical summary of the annotations indicating statistically significant (overrepresented) nodes.

Mary Dolan, Ph.D.
Bioinformatics Department, The Jackson Laboratory
NCGIA, Department of Spatial Information Science and Engineering, University of Maine
Boardman Hall 329
University of Maine
Orono, Maine 04469
fax: 207.581.2206
mdolan at
mary_dolan at

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