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New paper on GOTax platform

Andreas Schlicker andreas.schlicker at
Fri Mar 30 03:14:23 PDT 2007

Hi all,

we just published a paper about our new GOTax platform in Genome Biology.
It integrates proteins, protein families, GO, and the taxonomy, and allows 
searches combining the different data types. Additionally, it provides 
functional similarity measures based on GO.

You can find the paper at, and GOTax at

Here is the abstract:
We describe GOTax (, a comparative genomics 
platform that integrates protein annotation with protein family classification 
and taxonomy. User-defined sets of proteins, protein families, annotation terms 
or taxonomic groups can be selected and compared, allowing for the analysis of 
distribution of biological processes and molecular activities over different 
taxonomic groups. In particular, a measure of functional similarity is available 
for comparing proteins and protein families, establishing functional 
relationships independent of evolution.

Kind regards,

Andreas Schlicker, M.Sc.
Max-Planck-Institute for Informatics
Department 3: Computational Biology and Applied Algorithmics
Stuhlsatzenhausweg 85
66123 Saarbruecken

Phone: +49 681 9325 321
Fax: +49 681 9325 399

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