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[Gofriends] UniProtKB-GOA release [2010-12-14]

Tony Sawford tonys at
Tue Dec 14 05:11:50 PST 2010

UniProtKB-GOA release: 14 December 2010

UniProtKB-GOA (UniProtKB GO Annotation at EBI) is a project run by the 
European Bioinformatics Institute that provides assignments of gene 
products to the Gene Ontology (GO) resource.

The data can be obtained via:

           EBI FTP:

           EBI SRS: Search GOA data library

           GO FTP:

           GO CVS:

For further information read: or contact
goa at

Latest News

GOA proteomes files are now created using UniProtKB proteome data

As of this latest release, UniProtKB-GOA are creating the proteomes gene 
association files using the UniProtKB proteomes data. The UniProtKB-GOA 
proteomes files are available here:

The proteome sets provided by UniProtKB-GOA were previously based on 
those defined by the Integr8 project. Integr8 is planning to close after 
the launch of Ensembl Genomes as the next-generation interface for 
genome-scale data from non-vertebrate species. UniProtKB is taking over 
responsibility for the maintenance of the complete proteome sets, which 
can be found here:

There are two main consequences that should be noted:

1) The proteomes are available only for those species that have a 
complete genome, as defined by INSDC. For the complete genomes, please 
see and the NCBI Project database,

2) The entries within the proteome are the direct translation of the 
sequenced reference genome; this logic is applied to all species. Any 
species-specific rules that Integr8 used have not been propagated to the 
new sets. The proteome sets are subsets of the GOA-UniProt gene 
association file, and consequently if a protein accession is deemed not 
to be present in a particular proteome then any manual annotations made 
to this protein will not be visible in the proteome set; they will, 
however, still be available from the GOA-UniProt gene association file.

Compliments of the season,
UniProtKB-GOA Production

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