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[go-friends] UniProtKB-GOA release [2011-08-24]

Tony Sawford tonys at
Wed Aug 24 02:12:55 PDT 2011

UniProtKB-GOA release: 24 August 2011

UniProtKB-GOA (UniProtKB GO Annotation at EBI) is a project run by the 
European Bioinformatics Institute that provides assignments of gene 
products to the Gene Ontology (GO) resource.

The data can be obtained via:

           EBI FTP:

           EBI SRS: Search GOA data library

           GO FTP:

           GO CVS:

For further information read: or contact
goa at

Latest News

In this release, the UniProt GO annotation files contain a greatly 
reduced number of protein binding GO annotations from the IntAct 
database. A subset of presumed reliable interactions is now extracted 
from the IntAct dataset with export determined using a simple scoring 
system developed by IntAct, coupled to a score threshold that has been 
deliberately chosen to exclude interactions supported by only one 
experimental observation. Further details of how interactions are scored 
can be found at the IntAct website 
( This simple 
score-based filter is be used in combination with a set of defined rules 
that excludes certain types of data, such as interactions that have been 
inferred but not experimentally proven.

UniProtKB-GOA Production

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