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[Gofriends] UniProtKB-GOA release [2011-02-09]

Tony Sawford tonys at
Wed Feb 9 05:09:41 PST 2011

UniProtKB-GOA release: 09 February 2011

UniProtKB-GOA (UniProtKB GO Annotation at EBI) is a project run by the 
European Bioinformatics Institute that provides assignments of gene 
products to the Gene Ontology (GO) resource.

The data can be obtained via:

           EBI FTP:

           EBI SRS: Search GOA data library

           GO FTP:

           GO CVS:

For further information read: or contact
goa at

Latest News

Inferred Biological Process GO annotations now included in the 
UniProtKB-GOA annotation set.

We are pleased to announce an additional set of GO annotations available 
in this release that have automatically generated from the Molecular 
Function (MF) -> Biological Process (BP) inter-ontology relationships 
present in the GO OBO  v1.2 format.

As many GO users do not currently reason over the GO inter-ontology 
relationships, a set of inferred annotations has been generated to 
improve the consistency of the Biological Process annotation set. These 
GO annotations are produced when an annotation has been made (either 
manually or electronically) to a Molecular Function term that, either 
directly or via one of its parent terms, has a relationship to a 
Biological Process term and where the Process term (or one of its 
children) has not already been used in the annotation set for the same 
gene product identifier. This inferred annotation set applies the same 
gene product identifier, reference and evidence code as the asserted 
function annotation and are generated from all sources of GO 
annotations, with only 'NOT'-qualified annotations being excluded. All 
such inferred GO annotations can be identified by the 'GOC' value in the 
'assigned_by' field (column 15).

UniProtKB-GOA Production

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