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[Gofriends] UniProtKB-GOA release [2011-02-09]
tonys at ebi.ac.uk
Wed Feb 9 05:09:41 PST 2011
UniProtKB-GOA release: 09 February 2011
UniProtKB-GOA (UniProtKB GO Annotation at EBI) is a project run by the
European Bioinformatics Institute that provides assignments of gene
products to the Gene Ontology (GO) resource.
The data can be obtained via:
EBI FTP: ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/
EBI SRS: http://srs.ebi.ac.uk. Search GOA data library
GO FTP: ftp://ftp.geneontology.org/pub/go/gene-associations/
GO CVS: http://www.geneontology.org/GO.CVS.help.html
For further information read: http://www.ebi.ac.uk/GOA or contact
goa at ebi.ac.uk.
Inferred Biological Process GO annotations now included in the
UniProtKB-GOA annotation set.
We are pleased to announce an additional set of GO annotations available
in this release that have automatically generated from the Molecular
Function (MF) -> Biological Process (BP) inter-ontology relationships
present in the GO OBO v1.2 format.
As many GO users do not currently reason over the GO inter-ontology
relationships, a set of inferred annotations has been generated to
improve the consistency of the Biological Process annotation set. These
GO annotations are produced when an annotation has been made (either
manually or electronically) to a Molecular Function term that, either
directly or via one of its parent terms, has a relationship to a
Biological Process term and where the Process term (or one of its
children) has not already been used in the annotation set for the same
gene product identifier. This inferred annotation set applies the same
gene product identifier, reference and evidence code as the asserted
function annotation and are generated from all sources of GO
annotations, with only 'NOT'-qualified annotations being excluded. All
such inferred GO annotations can be identified by the 'GOC' value in the
'assigned_by' field (column 15).
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