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[go-friends] UniProt-GOA release [2012-05-16]

Carlos Bonilla carlos.bonilla at ebi.ac.uk
Wed May 16 05:36:37 PDT 2012


UniProt-GOA release:
=====================================

UniProt-GOA (UniProt GO Annotation) is a project run by the UniProt
group that provides assignments of gene products to the Gene Ontology
(GO) resource.

The data can be obtained via:

           EBI FTP:ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/

           EBI SRS:http://srs.ebi.ac.uk. Search GOA data library

           GO FTP:ftp://ftp.geneontology.org/pub/go/gene-associations/

           GO CVS:http://www.geneontology.org/GO.CVS.help.html

For further information read:http://www.ebi.ac.uk/GOA  or contact
goa at ebi.ac.uk.


Latest news
===========

1. New UniPathway2GO mapping provides an additional 113,285 GO annotations.

UniProt-GOA are pleased to announce that in collaboration with the Swiss
Institute of Bioinformatics, INRIA (Rhone-Alpes) and Laboratoire
d'Ecologie Alpine (Grenoble), we are able to offer an additional 113,285
GO annotations that describe the pathway(s) that 105,041 UniProtKB
entries are involved in. 48% of these annotations apply a GO term that
either uniquely describes a protein's involvement in a certain process,
or supplies a more granular term than is supplied by other UniProt
electronic annotation methods.

UniPathway is a manually curated resource of enzyme-catalyzed and
spontaneous chemical reactions that provides a hierarchical
representation of metabolic pathways. Descriptions of the pathway(s)
that a particular protein is involved in are included in UniProtKB
records. Further information on the UniPathway resource is available at
http://www.unipathway.org/obiwarehouse/unipathway.

So far, 425 UniPathway pathway terms have been manually mapped to GO
terms. The mapping is available from:
http://www.grenoble.prabi.fr/dev/obiwarehouse/download/unipathway/public/unipathway2go.tsv

The reference cited for these annotations is GO_REF:0000041 (for further
details see:
http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000041)

2. Inclusion of multiple identifiers in the 'with/from' column of
UniProt-GOA annotations

UniProt-GOA is able to include in this release those GO annotations that
have applied more than one identifier in the 'with/from' annotation
field (column 8 of the GAF2.0 format). This means that 12,317
annotations from external annotation groups are now more fully
represented in the UniProt-GOA files, ensuring we are able to provide a
more comprehensive set of GO annotations to users.


Regards,
UniProt-GOA Production



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