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[go-friends] UniProt-GOA release [2012-05-16]

Carlos Bonilla carlos.bonilla at
Wed May 16 05:36:37 PDT 2012

UniProt-GOA release:

UniProt-GOA (UniProt GO Annotation) is a project run by the UniProt
group that provides assignments of gene products to the Gene Ontology
(GO) resource.

The data can be obtained via:

           EBI FTP:

           EBI SRS: Search GOA data library

           GO FTP:

           GO CVS:

For further information read:  or contact
goa at

Latest news

1. New UniPathway2GO mapping provides an additional 113,285 GO annotations.

UniProt-GOA are pleased to announce that in collaboration with the Swiss
Institute of Bioinformatics, INRIA (Rhone-Alpes) and Laboratoire
d'Ecologie Alpine (Grenoble), we are able to offer an additional 113,285
GO annotations that describe the pathway(s) that 105,041 UniProtKB
entries are involved in. 48% of these annotations apply a GO term that
either uniquely describes a protein's involvement in a certain process,
or supplies a more granular term than is supplied by other UniProt
electronic annotation methods.

UniPathway is a manually curated resource of enzyme-catalyzed and
spontaneous chemical reactions that provides a hierarchical
representation of metabolic pathways. Descriptions of the pathway(s)
that a particular protein is involved in are included in UniProtKB
records. Further information on the UniPathway resource is available at

So far, 425 UniPathway pathway terms have been manually mapped to GO
terms. The mapping is available from:

The reference cited for these annotations is GO_REF:0000041 (for further
details see:

2. Inclusion of multiple identifiers in the 'with/from' column of
UniProt-GOA annotations

UniProt-GOA is able to include in this release those GO annotations that
have applied more than one identifier in the 'with/from' annotation
field (column 8 of the GAF2.0 format). This means that 12,317
annotations from external annotation groups are now more fully
represented in the UniProt-GOA files, ensuring we are able to provide a
more comprehensive set of GO annotations to users.

UniProt-GOA Production

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