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[go-friends] [Reactome-announce] Version 42 of Reactome Knowledgebase has been released.

Robin Haw Robin.Haw at oicr.on.ca
Mon Sep 24 10:12:57 PDT 2012


Topics with new or revised events include Immune system (STING mediated induction of type 1 IFN<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_147841.1> and DAP12 Interactions and signaling<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_147694.1>), Disease (Mucopolysaccharidoses<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=%20REACT_147853.1> and Signaling by PI3K/AKT in Cancer<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=%20REACT_147723.1>), Cell Cycle (Golgi Cisternae Pericentriolar Stack Reorganization<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=%20REACT_1100.3>), Metabolism (Regulation of Cholesterol Biosynthesis by SREBP<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_147797.1>), Metabolism of proteins (Metabolism of Angiotensinogen to Angiotensins<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_147707.1>), Membrane Trafficking (GLUT4 Translocation<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_147867.1>), and Gene expression. S Alves<http://www.ncbi.nlm.nih.gov/pubmed?term=Alves%20S%5BAuthor%5D&cauthor=true&cauthor_uid=22884962>, JL Ashworth<http://www.ncbi.nlm.nih.gov/pubmed?term=Jane%20L%20Ashworth[Author]>, A Colanzi<http://www.ncbi.nlm.nih.gov/pubmed?term=Antonino%20Colanzi[Author]>, MF Coutinho<http://www.ncbi.nlm.nih.gov/pubmed?term=Maria%20Francisca%20Coutinho[Author]>, L Jin<http://www.amc.edu/Research/IMD/imdresearcher.cfm?ID=429>, J Joseph<http://www.ncbi.nlm.nih.gov/pubmed?term=Joseph%20J[Author]&cauthor=true&cauthor_uid=22743190>, A Klip<http://www.ncbi.nlm.nih.gov/pubmed?term=Amira%20Klip[Author]>, LL Lanier<http://www.ncbi.nlm.nih.gov/pubmed?term=Lewis%20L%20Lanier[Author]>, G Liang<http://www.ncbi.nlm.nih.gov/pubmed?term=Guosheng%20Liang[Author]>, F Rauscher<http://www.ncbi.nlm.nih.gov/pubmed?term=Frank%20Rauscher[Author]>, L Thorpe<http://www.ncbi.nlm.nih.gov/pubmed?term=Lauren%20Thorpe[Author]>, Y Wang<http://www.ncbi.nlm.nih.gov/pubmed?term=Yanzhuang%20Wang[Author]>, H Yuzugullu<http://www.ncbi.nlm.nih.gov/pubmed?term=Haluk%20%20%20Yuzugullu[Author]>, and J Zhao<http://jeanzhao.dfci.harvard.edu/> are our external reviewers. New pathway illustrations for this release include Signal Transduction<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111102>, Signaling by Hippo<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_118607>, Signaling by SCF-KIT<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_111040>, and Mitochondrial Protein Import<http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_118595>. Reactome is hosting two webinars, Using Reactome Pathway Database<http://www.eventbrite.com/event/4277580358/eorg> and Reactome Functional Interaction Network plugin<http://www.eventbrite.com/event/4302759670/eorg> in October. If you are interesting in participating, please register at Eventbrite<http://reactome.eventbrite.com/>. A new paper entitled Reactome - a curated knowledgebase of biological pathways: megakaryocytes and platelets<http://www.ncbi.nlm.nih.gov/pubmed/22985186> has been published in the Journal of Thrombosis and Haemostasis<http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1538-7836>.
A full description of the new and updated pathways is available on the Reactome website at http://www.reactome.org<http://www.reactome.org/>

Reactome is a collaboration between groups at the Ontario Institute for Cancer Research, Cold Spring Harbor Laboratory, New York University Medical Center, and The European Bioinformatics Institute. Freely available to everyone worldwide, the Reactome database offers pathway data encapsulating areas of human biology ranging from metabolism to complex events such as FGFR signaling, apoptosis and disease, extracted from the published literature by Reactome curatorial staff and cross-referenced to a wide range of standard biological databases. Reactome data and software are distributed under the terms of the Creative Commons Attribution 3.0 Unported License.

For more information contact:
Robin Haw
Email: help at reactome.org<https://lists.reactome.org/mailman/listinfo/reactome-announce>
Tel: 647-260-7985


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