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[go-friends] [go] Alert: Proposal to obsolete GO:0004158, : term that impacts existing annotation

Dr Midori A. Harris mah79 at
Fri May 9 01:56:26 PDT 2014

The PomBase annotation will go away when the InterPro2go mapping is 
deleted, so it's all fine with us.


On Thu, 8 May 2014, Harold Drabkin wrote:

> The term GO:0004158, dihydroorotate oxidase I,( Catalysis of the reaction: (S)-dihydroorotate + O(2) = H(2)O(2) +orotate.), which was mapped to EC , is scheduled to be made obsolete.
> EC has determined that this reaction in fact does not exist. They have withdrawn EC
> There are currently 65 total annotations directly to this term.
> IDA: 1
> 1, RGD to Dhodh
> ISS: 21:
> 1MGI,  1 UniProtKB, one JCVI_CMR, and the remaining TIGR_CMR.
> IEA: 41;
> 21 UniProtKB, 2 Flybase, 1 MGI, 10 CGD, 1 AspGD, 2 Zfin, 1 RGD, 1 SGD, 1 Pombe, 1 dictybase
> All mappings to EC2GO, IP2GO, and SP_KW2GO should be removed. The term has a mapping in IP2GO (hence the IEAs); It is used in the catalytic slim subset (and thus will be removed).
> Note: If fumarate is not shown to be nvolved, you may want to consider GO:0004152, dihydroorotate dehydrogenase activity (parent term); if the reaction involves fumarate, then use GO:0052888 dihydroorotate oxidase (fumarate) activity
> See SF 10770 for details.
> The deadline for comments is 5/20/14  If we hear nothing, the obsoletion goes ahead --
> ________________
> Harold J Drabkin, Ph.D.
> Senior Scientific Curator
> Mouse Genome Informatics
> The Jackson Laboratory
> 600 Main Street
> Bar Harbor, ME 04609
> voice:207-288-6650
> fax: 207-288-6131
> Email: harold.drabkin at<mailto:harold.drabkin at>
> The information in this email, including attachments, may be confidential and is intended solely for the addressee(s). If you believe you received this email by mistake, please notify the sender by return email as soon as possible.

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