<html xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns="http://www.w3.org/TR/REC-html40">

<head>
<meta http-equiv=Content-Type content="text/html; charset=us-ascii">
<meta name=Generator content="Microsoft Word 11 (filtered medium)">
<style>
<!--
 /* Style Definitions */
 p.MsoNormal, li.MsoNormal, div.MsoNormal
        {margin:0in;
        margin-bottom:.0001pt;
        font-size:12.0pt;
        font-family:"Times New Roman";}
a:link, span.MsoHyperlink
        {color:blue;
        text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
        {color:purple;
        text-decoration:underline;}
p
        {mso-margin-top-alt:auto;
        margin-right:0in;
        mso-margin-bottom-alt:auto;
        margin-left:0in;
        font-size:12.0pt;
        font-family:"Times New Roman";}
span.EmailStyle17
        {mso-style-type:personal-compose;
        font-family:Arial;
        color:windowtext;}
@page Section1
        {size:8.5in 11.0in;
        margin:1.0in 1.25in 1.0in 1.25in;}
div.Section1
        {page:Section1;}
 /* List Definitions */
 @list l0
        {mso-list-id:1477333944;
        mso-list-type:hybrid;
        mso-list-template-ids:191510212 67698703 67698713 67698715 67698703 67698713 67698715 67698703 67698713 67698715;}
@list l0:level1
        {mso-level-tab-stop:.5in;
        mso-level-number-position:left;
        text-indent:-.25in;}
ol
        {margin-bottom:0in;}
ul
        {margin-bottom:0in;}
-->
</style>

</head>

<body lang=EN-US link=blue vlink=purple>

<div class=Section1>

<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'>In an effort to keep in line with the goals of the Gene
Ontology Consortium and to increase our contributions to the project, RGD has focused
its efforts in the past couple of months on improving our overall system for
handling all aspects of GO.  I am pleased to announce that RGD now has in
place:<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'><o:p> </o:p></span></font></p>

<ol style='margin-top:0in' start=1 type=1>
 <li class=MsoNormal style='mso-list:l0 level1 lfo1'><font size=2 face=Arial><span
     style='font-size:10.0pt;font-family:Arial'>incorporation of daily updates of
     the Gene Ontology at RGD to ensure our curators are using the latest
     version of GO at all times<o:p></o:p></span></font></li>
 <li class=MsoNormal style='mso-list:l0 level1 lfo1'><font size=2 face=Arial><span
     style='font-size:10.0pt;font-family:Arial'>weekly submission of gene
     association files from RGD to GO to improve the currency of RGD annotations
     available at GO <o:p></o:p></span></font></li>
 <li class=MsoNormal style='mso-list:l0 level1 lfo1'><font size=2 face=Arial><span
     style='font-size:10.0pt;font-family:Arial'>improved curation software to
     increase efficiency and accuracy of RGD GO annotations<o:p></o:p></span></font></li>
 <li class=MsoNormal style='mso-list:l0 level1 lfo1'><font size=2 face=Arial><span
     style='font-size:10.0pt;font-family:Arial'>automated retrieval of
     annotations to obsolete terms into the curation software for easy
     re-assignment to the appropriate GO term<o:p></o:p></span></font></li>
</ol>

<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'><o:p> </o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'>These developments, along with our continued focus on
curator training and standardization of procedures and policies in alignment
with those of the GO consortium, illustrate our commitment to GO annotation as
a cornerstone of our curation efforts will provide the research community with better
and more comprehensive information on rat genes.<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'><o:p> </o:p></span></font></p>

<p><font size=2 face=Arial><span style='font-size:10.0pt;font-family:Arial'>Mary
Shimoyama</span></font> <br>
<font size=2 face=Arial><span style='font-size:10.0pt;font-family:Arial'>Program
Manager</span></font> <br>
<font size=2 face=Arial><span style='font-size:10.0pt;font-family:Arial'>Rat
Genome Database</span></font> <br>
<font size=2 face=Arial><span style='font-size:10.0pt;font-family:Arial'>Human
and Molecular Genetics Center</span></font> <br>
<font size=2 face=Arial><span style='font-size:10.0pt;font-family:Arial'>Medical
College of Wisconsin</span></font> <br>
<font size=2 face=Arial><span style='font-size:10.0pt;font-family:Arial'>414-456-7505</span></font>
<br>
<font size=2 face=Arial><span style='font-size:10.0pt;font-family:Arial'>shimoyama@mcw.edu</span></font><br>
<font size=2 face=Arial><span style='font-size:10.0pt;font-family:Arial'><a
href="http://rgd.mcw.edu/" target="_blank">http://rgd.mcw.edu/</a></span></font>
<o:p></o:p></p>

<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'><o:p> </o:p></span></font></p>

</div>

</body>

</html>