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[go-helpdesk] Fwd: Re: [go-friends] GO enrichment analysis - IDs not in database
Paola Roncaglia
paola at ebi.ac.uk
Thu Jun 28 13:10:09 PDT 2012
For archive.
Paola
-------- Original Message --------
Subject: Re: [go-friends] GO enrichment analysis - IDs not in database
Date: Thu, 28 Jun 2012 13:00:45 -0700
From: Nathan Salomonis <nsalomonis at gladstone.ucsf.edu>
To: Paola Roncaglia <paola at ebi.ac.uk>
Great!
Nathan
On 6/28/12 12:52 PM, "Paola Roncaglia"<paola at ebi.ac.uk> wrote:
> Dear Nathan,
>
> Many thanks for your suggestions. I am forwarding your email to our user
> who might contact you directly if needed.
>
> With best regards,
> Paola Roncaglia
>
> On 6/28/12 5:29 PM, Nathan Salomonis wrote:
>> I would also like to recommend our software GO-Elite:
>> http://genmapp.org/go_elite
>>
>> GO-Elite is a flexible platform that can create databases easily for any
>> species using its graphical user interface. All that is needed are a couple
>> of tab-delimited text files. These will include a gene to GO or gene to
>> pathway association file, gene annotation file (symbol and description) and
>> optionally an indirect identifier to curated gene identifier (model organism
>> database ID or MOD) table (e.g., Affymetrix ID to MGI). Gene Ontology
>> hierarchy relationships can be automatically imported and updated as well
>> from any source you like. A tutorial for adding new species support is
>> provided here:
>> http://code.google.com/p/go-elite/wiki/Tutorial_Adding_New_Species
>> Also see:
>> http://genmapp.org/go_elite/help.htm#new_species
>>
>> If you want a quick way to identify putative enriched biological GO terms or
>> biological pathways you can also provide orthologous gene symbols as your
>> input and denominator identifiers (SystemCode: Sy), after downloading the
>> appropriate orthologous species database.
>>
>> You can check out our paper at:
>> http://bioinformatics.oxfordjournals.org/content/early/2012/06/27/bioinforma
>> tics.bts366
>>
>> Let us know if you have any questions.
>>
>> Best,
>> Nathan
>>
>>
>> On 6/28/12 8:48 AM, "Paola Roncaglia"<paola at ebi.ac.uk> wrote:
>>
>>> Hello,
>>>
>>> We have a GO user (cc'd on this email) who would like to perform GO term
>>> enrichment analysis on a newly sequenced species, from in-house
>>> microarray results. The genomic data is public (released by DOE-JGI),
>>> but not available from a public database yet, therefore the gene product
>>> IDs are not recognized by e.g. AmiGO's enrichment tool. The user has a
>>> list of IDs of differentially expressed transcript, and a table provided
>>> by the sequencing lab that contains all transcript IDs and
>>> automatically-generated GO term assignments. Could anyone please
>>> recommend a tool?
>>>
>>> The latest email on this subject (containing most of the pertaining
>>> GO-help correspondence, bottom to top) is here:
>>> https://mailman.stanford.edu/pipermail/go-helpdesk/2012-June/005212.html
>>>
>>> Many thanks,
>>> Paola Roncaglia
>>
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