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[go-ontology] GO:0044387 "negative regulation of protein kinase activity by regulation of protein phosphorylation"

Chris Mungall cjmungall at lbl.gov
Tue Dec 20 12:44:29 PST 2011


I went ahead and removed the logical definition.

GO is back to a blue ball in Jenkins:

http://ladle.lbl.gov:8080/job/build-go/lastSuccessfulBuild/

The first TG1 commit also went through fine

On Dec 17, 2011, at 8:46 AM, Jane Lomax wrote:

> Yep - was from this SF item:
> 
> https://sourceforge.net/tracker/?func=detail&aid=3418423&group_id=36855&atid=440764
> 
> in retrospect it's obvious that xp wouldn't work - I'm not having a good week! I'll remove the xp.
> 
> Jane
> 
> On 16/12/2011 20:48, Chris Mungall wrote:
>> Was this term intentional?
>> 
>> with the current logical definition, it's inferred to be equivalent to:
>> 	GO:0006469 "negative regulation of protein kinase activity"
>> 
>> Which could potentially cause various downstream problems in the reasoning.
>> 
>> Sorry, I didn't think through the regulation-by pattern. In retrospect it's obvious problem like this would show up.
>> 
>> I suggest removing the logical definition for this term for now and manually classifying it.
>> 
>> The simplest short-medium term solution is to introduce a sub-relation of regulates, I think.
>> 
>> Maybe a good exercise for the workshop.
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